Synthesis and preliminary cytotoxicity study of a cephalosporin-CC-1065 analogue prodrug

BACKGROUND: Antibody-directed enzyme prodrug therapy (ADEPT) is a promising new approach to deliver anticancer drugs selectively to tumor cells. In this approach, an enzyme is conjugated to a tumor-specific antibody. The antibody selectively localizes the enzyme to the tumor cell surface. Subsequent...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yuqiang, Yuan, Huiling, Wright, Susan C, Wang, Hong, Larrick, James W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC59845/
https://www.ncbi.nlm.nih.gov/pubmed/11710971
http://dx.doi.org/10.1186/1472-6769-1-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC59845/
https://www.ncbi.nlm.nih.gov/pubmed/11710971
http://dx.doi.org/10.1186/1472-6769-1-4

Ejemplares similares