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Synthesis and preliminary cytotoxicity study of a cephalosporin-CC-1065 analogue prodrug
BACKGROUND: Antibody-directed enzyme prodrug therapy (ADEPT) is a promising new approach to deliver anticancer drugs selectively to tumor cells. In this approach, an enzyme is conjugated to a tumor-specific antibody. The antibody selectively localizes the enzyme to the tumor cell surface. Subsequent...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2001
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC59845/ https://www.ncbi.nlm.nih.gov/pubmed/11710971 http://dx.doi.org/10.1186/1472-6769-1-4 |