Cargando…
Suppression of Slit3 induces tumor proliferation and chemoresistance in hepatocellular carcinoma through activation of GSK3β/β-catenin pathway
BACKGROUND: It is essential to understand the mechanisms responsible for hepatocellular carcinoma (HCC) progression and chemoresistance in order to identify prognostic biomarkers as well as potential therapeutic avenues. Recent findings have shown that SLIT3 appears to function as a novel tumor supp...
Autores principales: | Ng, Lui, Chow, Ariel K. M., Man, Johnny H. W., Yau, Thomas C. C., Wan, Timothy M. H., Iyer, Deepak N., Kwan, Virginia H. T., Poon, Ronnie T. P., Pang, Roberta W. C., Law, Wai-Lun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984734/ https://www.ncbi.nlm.nih.gov/pubmed/29859044 http://dx.doi.org/10.1186/s12885-018-4326-5 |
Ejemplares similares
-
Osteopontin Overexpression Induced Tumor Progression and Chemoresistance to Oxaliplatin through Induction of Stem-Like Properties in Human Colorectal Cancer
por: Ng, Lui, et al.
Publicado: (2015) -
Slit2 Inactivates GSK3β to Signal Neurite Outgrowth Inhibition
por: Byun, Justin, et al.
Publicado: (2012) -
Gas6/Axl Axis Contributes to Chemoresistance and Metastasis in Breast Cancer through Akt/GSK-3β/β-catenin Signaling
por: Wang, Cun, et al.
Publicado: (2016) -
20(S)-protopanaxadiol promotes the migration, proliferation, and differentiation of neural stem cells by targeting GSK-3β in the Wnt/GSK-3β/β-catenin pathway
por: Lin, Kaili, et al.
Publicado: (2020) -
Chaperonin-Containing TCP-1 Promotes Cancer Chemoresistance and Metastasis through the AKT-GSK3β-β-Catenin and XIAP-Survivin Pathways
por: Chang, Yun-Xun, et al.
Publicado: (2020)