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Selective pharmacological inhibition of DDR1 prevents experimentally-induced glomerulonephritis in prevention and therapeutic regime

BACKGROUND: Discoidin domain receptor 1 (DDR1) is a collagen-activated receptor tyrosine kinase extensively implicated in diseases such as cancer, atherosclerosis and fibrosis. Multiple preclinical studies, performed using either a gene deletion or a gene silencing approaches, have shown this recept...

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Detalles Bibliográficos
Autores principales:	Moll, Solange, Yasui, Yukari, Abed, Ahmed, Murata, Takeshi, Shimada, Hideaki, Maeda, Akira, Fukushima, Naoshi, Kanamori, Masakazu, Uhles, Sabine, Badi, Laura, Cagarelli, Thomas, Formentini, Ivan, Drawnel, Faye, Georges, Guy, Bergauer, Tobias, Gasser, Rodolfo, Bonfil, R. Daniel, Fridman, Rafael, Richter, Hans, Funk, Juergen, Moeller, Marcus J., Chatziantoniou, Christos, Prunotto, Marco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984769/ https://www.ncbi.nlm.nih.gov/pubmed/29859097 http://dx.doi.org/10.1186/s12967-018-1524-5

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