GABAergic deficits and schizophrenia-like behaviors in a mouse model carrying patient-derived neuroligin-2 R215H mutation

Schizophrenia (SCZ) is a severe mental disorder characterized by delusion, hallucination, and cognitive deficits. We have previously identified from schizophrenia patients a loss-of-function mutation Arg(215)→His(215) (R215H) of neuroligin 2 (NLGN2) gene, which encodes a cell adhesion molecule criti...

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Detalles Bibliográficos
Autores principales: Jiang, Dong-Yun, Wu, Zheng, Forsyth, Cody Tieu, Hu, Yi, Yee, Siu-Pok, Chen, Gong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984814/
https://www.ncbi.nlm.nih.gov/pubmed/29859117
http://dx.doi.org/10.1186/s13041-018-0375-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984814/
https://www.ncbi.nlm.nih.gov/pubmed/29859117
http://dx.doi.org/10.1186/s13041-018-0375-6

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