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GABAergic deficits and schizophrenia-like behaviors in a mouse model carrying patient-derived neuroligin-2 R215H mutation
Schizophrenia (SCZ) is a severe mental disorder characterized by delusion, hallucination, and cognitive deficits. We have previously identified from schizophrenia patients a loss-of-function mutation Arg(215)→His(215) (R215H) of neuroligin 2 (NLGN2) gene, which encodes a cell adhesion molecule criti...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984814/ https://www.ncbi.nlm.nih.gov/pubmed/29859117 http://dx.doi.org/10.1186/s13041-018-0375-6 |