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Complement components are upregulated and correlate with disease progression in the TDP-43(Q331K) mouse model of amyotrophic lateral sclerosis

BACKGROUND: Components of the innate immune complement system have been implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS) specifically using hSOD1 transgenic animals; however, a comprehensive examination of complement expression in other transgenic ALS models has not been perform...

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Detalles Bibliográficos
Autores principales:	Lee, John D., Levin, Samantha C., Willis, Emily F., Li, Rui, Woodruff, Trent M., Noakes, Peter G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984816/ https://www.ncbi.nlm.nih.gov/pubmed/29859100 http://dx.doi.org/10.1186/s12974-018-1217-2

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