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Contactin-2, a synaptic and axonal protein, is reduced in cerebrospinal fluid and brain tissue in Alzheimer’s disease

BACKGROUND: Synaptic and axonal loss are two major mechanisms underlying Alzheimer’s disease (AD) pathogenesis, and biomarkers reflecting changes in these cellular processes are needed for early diagnosis and monitoring the progression of AD. Contactin-2 is a synaptic and axonal membrane protein tha...

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Detalles Bibliográficos
Autores principales:	Chatterjee, Madhurima, Del Campo, Marta, Morrema, Tjado H. J., de Waal, Matthijs, van der Flier, Wiesje M., Hoozemans, Jeroen J. M., Teunissen, Charlotte E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984818/ https://www.ncbi.nlm.nih.gov/pubmed/29859129 http://dx.doi.org/10.1186/s13195-018-0383-x

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