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The LepR-mediated leptin transport across brain barriers controls food reward

OBJECTIVE: Leptin is a key hormone in the control of appetite and body weight. Predominantly produced by white adipose tissue, it acts on the brain to inhibit homeostatic feeding and food reward. Leptin has free access to circumventricular organs, such as the median eminence, but entry into other br...

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Detalles Bibliográficos
Autores principales: Di Spiezio, Alessandro, Sandin, Elvira Sonia, Dore, Riccardo, Müller-Fielitz, Helge, Storck, Steffen E., Bernau, Mareike, Mier, Walter, Oster, Henrik, Jöhren, Olaf, Pietrzik, Claus U., Lehnert, Hendrik, Schwaninger, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985039/
https://www.ncbi.nlm.nih.gov/pubmed/29254602
http://dx.doi.org/10.1016/j.molmet.2017.12.001