Cargando…
Using Drosophila Models of Amyloid Toxicity to Study Autophagy in the Pathogenesis of Alzheimer's Disease
Autophagy is a conserved catabolic pathway that involves the engulfment of cytoplasmic components such as large protein aggregates and organelles that are delivered to the lysosome for degradation. This process is important in maintaining neuronal function and raises the possibility of a role for au...
Autores principales: | O'Keefe, Louise, Denton, Donna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985114/ https://www.ncbi.nlm.nih.gov/pubmed/29888266 http://dx.doi.org/10.1155/2018/5195416 |
Ejemplares similares
-
Phenotypic analysis of a transgenic Drosophila model of Alzheimer’s amyloid-β toxicity
por: Sekiya, Michiko, et al.
Publicado: (2021) -
GULP1/CED-6 ameliorates amyloid-β toxicity in a Drosophila model of Alzheimer’s disease
por: Vivien Chiu, Wai Yin, et al.
Publicado: (2017) -
Amyloid Peptide Toxicity in an Animal Model of Alzheimer Disease
por: Gross, Liza
Publicado: (2007) -
Fenton chemistry and oxidative stress mediate the toxicity of the β-amyloid peptide in a Drosophila model of Alzheimer’s disease
por: Rival, Thomas, et al.
Publicado: (2009) -
Alzheimer’s disease: amyloid-based pathogenesis and potential therapies
por: Zhou, Yixiu, et al.
Publicado: (2018)