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Using Drosophila Models of Amyloid Toxicity to Study Autophagy in the Pathogenesis of Alzheimer's Disease

Autophagy is a conserved catabolic pathway that involves the engulfment of cytoplasmic components such as large protein aggregates and organelles that are delivered to the lysosome for degradation. This process is important in maintaining neuronal function and raises the possibility of a role for au...

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Detalles Bibliográficos
Autores principales: O'Keefe, Louise, Denton, Donna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985114/
https://www.ncbi.nlm.nih.gov/pubmed/29888266
http://dx.doi.org/10.1155/2018/5195416

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