Nanoparticles Prepared From N,N-Dimethyl-N-Octyl Chitosan as the Novel Approach for Oral Delivery of Insulin: Preparation, Statistical Optimization and In-vitro Characterization

In this study, N,N-Dimethyl-N-Octyl chitosan was synthesized. Nanoparticles containing insulin were prepared using PEC method and were statistically optimized using the Box-Behnken response surface methodology. The independent factors were considered to be the insulin concentration, concentration an...

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Detalles Bibliográficos
Autores principales: Shamsa, Elnaz Sadat, Mahjub, Reza, Mansoorpour, Maryam, Rafiee-Tehrani, Morteza, Abedin Dorkoosh, Farid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985163/
https://www.ncbi.nlm.nih.gov/pubmed/29881403

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