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Introduction of Human Flt3-L and GM-CSF into Humanized Mice Enhances the Reconstitution and Maturation of Myeloid Dendritic Cells and the Development of Foxp3(+)CD4(+) T Cells

Two cytokines, fms-related tyrosine kinase 3 ligand (Flt3-L) and granulocyte-macrophage colony-stimulating factor (GM-CSF) are considered to be the essential regulators of dendritic cell (DC) development in vivo. However, the combined effect of Flt3-L and GM-CSF on human DCs has not been evaluated i...

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Detalles Bibliográficos
Autores principales:	Iwabuchi, Ryutaro, Ikeno, Shota, Kobayashi-Ishihara, Mie, Takeyama, Haruko, Ato, Manabu, Tsunetsugu-Yokota, Yasuko, Terahara, Kazutaka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985304/ https://www.ncbi.nlm.nih.gov/pubmed/29892279 http://dx.doi.org/10.3389/fimmu.2018.01042

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