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Antibiotic Resistance Mediated by the MacB ABC Transporter Family: A Structural and Functional Perspective

The MacB ABC transporter forms a tripartite efflux pump with the MacA adaptor protein and TolC outer membrane exit duct to expel antibiotics and export virulence factors from Gram-negative bacteria. Here, we review recent structural and functional data on MacB and its homologs. MacB has a fold that...

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Detalles Bibliográficos
Autores principales:	Greene, Nicholas P., Kaplan, Elise, Crow, Allister, Koronakis, Vassilis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985334/ https://www.ncbi.nlm.nih.gov/pubmed/29892271 http://dx.doi.org/10.3389/fmicb.2018.00950

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