Cargando…
Essential Roles for Mannose-Binding Lectin-Associated Serine Protease-1/3 in the Development of Lupus-Like Glomerulonephritis in MRL/lpr Mice
The complement system, composed of the three activation pathways, has both protective and pathogenic roles in the development of systemic lupus erythematosus (or lupus), a prototypic autoimmune disease. The classical pathway contributes to the clearance of immune complexes (ICs) and apoptotic cells,...
Autores principales: | Machida, Takeshi, Sakamoto, Natsumi, Ishida, Yumi, Takahashi, Minoru, Fujita, Teizo, Sekine, Hideharu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985374/ https://www.ncbi.nlm.nih.gov/pubmed/29892304 http://dx.doi.org/10.3389/fimmu.2018.01191 |
Ejemplares similares
-
Mouse Ficolin B Has an Ability to Form Complexes with Mannose-Binding Lectin-Associated Serine Proteases and Activate Complement through the Lectin Pathway
por: Endo, Yuichi, et al.
Publicado: (2012) -
Essential role of Mannose-binding lectin-associated serine protease-1 in activation of the complement factor D
por: Takahashi, Minoru, et al.
Publicado: (2010) -
The complex formation of MASP-3 with pattern recognition molecules of the lectin complement pathway retains MASP-3 in the circulation
por: Kusakari, Kohei, et al.
Publicado: (2022) -
IgG3 deficiency extends lifespan and attenuates progression of glomerulonephritis in MRL/lpr mice
por: Greenspan, Neil S, et al.
Publicado: (2012) -
Knockout of the KH-Type Splicing Regulatory Protein Drives Glomerulonephritis in MRL-Fas(lpr) Mice
por: Schmidtke, Lisa, et al.
Publicado: (2021)