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Exposure of Human CD8(+) T Cells to Type-2 Cytokines Impairs Division and Differentiation and Induces Limited Polarization

Effector CD8(+) T cells generally produce type-1 cytokines and mediators of the perforin/granzyme cytolytic pathway, yet type-2-polarized CD8(+) cells (Tc2) are detected in type-2 (T2) cytokine-driven diseases such as asthma. It is unclear whether T2 cytokine exposure during activation is sufficient...

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Detalles Bibliográficos
Autores principales:	Fox, Annette, Harland, Kim L., Kedzierska, Katherine, Kelso, Anne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985406/ https://www.ncbi.nlm.nih.gov/pubmed/29892290 http://dx.doi.org/10.3389/fimmu.2018.01141

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