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Associations between smoking and lipid/lipoprotein concentrations among US adults aged ≥20 years

Cross-sectional data from National Health and Nutrition Examination Survey for the years 1999–2012 for those aged ≥20 years, fasting for at least 8 h, and classified as smokers and nonsmokers on the basis of observed serum cotinine levels were used to evaluate the impact of smoking on the adjusted a...

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Autores principales: Jain, Ram B, Ducatman, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985545/
https://www.ncbi.nlm.nih.gov/pubmed/29899809
http://dx.doi.org/10.1177/1849454418779310
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author Jain, Ram B
Ducatman, Alan
author_facet Jain, Ram B
Ducatman, Alan
author_sort Jain, Ram B
collection PubMed
description Cross-sectional data from National Health and Nutrition Examination Survey for the years 1999–2012 for those aged ≥20 years, fasting for at least 8 h, and classified as smokers and nonsmokers on the basis of observed serum cotinine levels were used to evaluate the impact of smoking on the adjusted and unadjusted concentrations of low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, total cholesterol (TC), and triglycerides (TG). Adjustments were made for the effects of gender; race/ethnicity; survey year; dietary intake of alcohol; caffeine; cholesterol; saturated, unsaturated, and total fatty acids; fasting time; body mass index; and poverty income ratio. Adjusted levels of LDL and TC did not vary among smokers and nonsmokers. Smokers had lower adjusted levels of HDL than nonsmokers (48.8 vs. 51.4 mg/dL, p < 0.01) and higher adjusted levels of TG (124.4 vs. 111.9 mg/dL, p < 0.01) than nonsmokers. Adjusted odds of smokers having abnormal levels were 1.6 (95% confidence interval (CI) 1.4–1.8) for HDL, 1.2 (95% CI 1.1–1.4) for TC, and 1.3 (95% CI 1.2–1.5) for TG. Males had lower adjusted levels than females for HDL (45.2 vs. 55.4 mg/dL, p < 0.01) and TC (191.3 vs. 196.6 mg/dL, p < 0.01) but higher adjusted levels than females for TG (126.3 vs. 110.1 mg/dL, p < 0.01) and LDL (114.4 vs. 112.6 mg/dL, p = 0.02). A unit increase in body mass index was associated with 1.4% decrease in the adjusted levels of HDL, 0.18% increase in the adjusted levels of LDL, and a 2.3% increase in the adjusted levels of TG.
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spelling pubmed-59855452018-06-13 Associations between smoking and lipid/lipoprotein concentrations among US adults aged ≥20 years Jain, Ram B Ducatman, Alan J Circ Biomark Research Article Cross-sectional data from National Health and Nutrition Examination Survey for the years 1999–2012 for those aged ≥20 years, fasting for at least 8 h, and classified as smokers and nonsmokers on the basis of observed serum cotinine levels were used to evaluate the impact of smoking on the adjusted and unadjusted concentrations of low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, total cholesterol (TC), and triglycerides (TG). Adjustments were made for the effects of gender; race/ethnicity; survey year; dietary intake of alcohol; caffeine; cholesterol; saturated, unsaturated, and total fatty acids; fasting time; body mass index; and poverty income ratio. Adjusted levels of LDL and TC did not vary among smokers and nonsmokers. Smokers had lower adjusted levels of HDL than nonsmokers (48.8 vs. 51.4 mg/dL, p < 0.01) and higher adjusted levels of TG (124.4 vs. 111.9 mg/dL, p < 0.01) than nonsmokers. Adjusted odds of smokers having abnormal levels were 1.6 (95% confidence interval (CI) 1.4–1.8) for HDL, 1.2 (95% CI 1.1–1.4) for TC, and 1.3 (95% CI 1.2–1.5) for TG. Males had lower adjusted levels than females for HDL (45.2 vs. 55.4 mg/dL, p < 0.01) and TC (191.3 vs. 196.6 mg/dL, p < 0.01) but higher adjusted levels than females for TG (126.3 vs. 110.1 mg/dL, p < 0.01) and LDL (114.4 vs. 112.6 mg/dL, p = 0.02). A unit increase in body mass index was associated with 1.4% decrease in the adjusted levels of HDL, 0.18% increase in the adjusted levels of LDL, and a 2.3% increase in the adjusted levels of TG. SAGE Publications 2018-05-31 /pmc/articles/PMC5985545/ /pubmed/29899809 http://dx.doi.org/10.1177/1849454418779310 Text en © The Author(s) 2018 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Research Article
Jain, Ram B
Ducatman, Alan
Associations between smoking and lipid/lipoprotein concentrations among US adults aged ≥20 years
title Associations between smoking and lipid/lipoprotein concentrations among US adults aged ≥20 years
title_full Associations between smoking and lipid/lipoprotein concentrations among US adults aged ≥20 years
title_fullStr Associations between smoking and lipid/lipoprotein concentrations among US adults aged ≥20 years
title_full_unstemmed Associations between smoking and lipid/lipoprotein concentrations among US adults aged ≥20 years
title_short Associations between smoking and lipid/lipoprotein concentrations among US adults aged ≥20 years
title_sort associations between smoking and lipid/lipoprotein concentrations among us adults aged ≥20 years
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985545/
https://www.ncbi.nlm.nih.gov/pubmed/29899809
http://dx.doi.org/10.1177/1849454418779310
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