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Dual polarity MALDI imaging mass spectrometry on the same pixel points reveals spatial lipid localizations at high-spatial resolutions in rat small intestine
Sensitive laser desorption/ionization obtained via a sublimation-coated 1,5-diaminonaphthalene (1,5-DAN) matrix allowed dual polarity MALDI-IMS analysis on the same pixel points across the jejunal mucosal region in rat small intestine which yielded high-spatial-resolution (10 μm) ion images of sever...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985652/ https://www.ncbi.nlm.nih.gov/pubmed/31490465 http://dx.doi.org/10.1039/c8ay00645h |
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author | Kaya, Ibrahim Jennische, Eva Lange, Stefan Malmberg, Per |
author_facet | Kaya, Ibrahim Jennische, Eva Lange, Stefan Malmberg, Per |
author_sort | Kaya, Ibrahim |
collection | PubMed |
description | Sensitive laser desorption/ionization obtained via a sublimation-coated 1,5-diaminonaphthalene (1,5-DAN) matrix allowed dual polarity MALDI-IMS analysis on the same pixel points across the jejunal mucosal region in rat small intestine which yielded high-spatial-resolution (10 μm) ion images of several lipid species correlated with the same histological features. |
format | Online Article Text |
id | pubmed-5985652 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Royal Society of Chemistry |
record_format | MEDLINE/PubMed |
spelling | pubmed-59856522018-06-15 Dual polarity MALDI imaging mass spectrometry on the same pixel points reveals spatial lipid localizations at high-spatial resolutions in rat small intestine Kaya, Ibrahim Jennische, Eva Lange, Stefan Malmberg, Per Anal Methods Chemistry Sensitive laser desorption/ionization obtained via a sublimation-coated 1,5-diaminonaphthalene (1,5-DAN) matrix allowed dual polarity MALDI-IMS analysis on the same pixel points across the jejunal mucosal region in rat small intestine which yielded high-spatial-resolution (10 μm) ion images of several lipid species correlated with the same histological features. Royal Society of Chemistry 2018-06-07 2018-05-03 /pmc/articles/PMC5985652/ /pubmed/31490465 http://dx.doi.org/10.1039/c8ay00645h Text en This journal is © The Royal Society of Chemistry 2018 http://creativecommons.org/licenses/by-nc/3.0/ This article is freely available. This article is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported Licence (CC BY-NC 3.0) |
spellingShingle | Chemistry Kaya, Ibrahim Jennische, Eva Lange, Stefan Malmberg, Per Dual polarity MALDI imaging mass spectrometry on the same pixel points reveals spatial lipid localizations at high-spatial resolutions in rat small intestine |
title | Dual polarity MALDI imaging mass spectrometry on the same pixel points reveals spatial lipid localizations at high-spatial resolutions in rat small intestine
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title_full | Dual polarity MALDI imaging mass spectrometry on the same pixel points reveals spatial lipid localizations at high-spatial resolutions in rat small intestine
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title_fullStr | Dual polarity MALDI imaging mass spectrometry on the same pixel points reveals spatial lipid localizations at high-spatial resolutions in rat small intestine
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title_full_unstemmed | Dual polarity MALDI imaging mass spectrometry on the same pixel points reveals spatial lipid localizations at high-spatial resolutions in rat small intestine
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title_short | Dual polarity MALDI imaging mass spectrometry on the same pixel points reveals spatial lipid localizations at high-spatial resolutions in rat small intestine
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title_sort | dual polarity maldi imaging mass spectrometry on the same pixel points reveals spatial lipid localizations at high-spatial resolutions in rat small intestine |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985652/ https://www.ncbi.nlm.nih.gov/pubmed/31490465 http://dx.doi.org/10.1039/c8ay00645h |
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