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A new mouse model of ARX dup24 recapitulates the patients’ behavioral and fine motor alterations

The aristaless-related homeobox (ARX) transcription factor is involved in the development of GABAergic and cholinergic neurons in the forebrain. ARX mutations have been associated with a wide spectrum of neurodevelopmental disorders in humans, among which the most frequent, a 24 bp duplication in th...

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Detalles Bibliográficos
Autores principales:	Dubos, Aline, Meziane, Hamid, Iacono, Giovanni, Curie, Aurore, Riet, Fabrice, Martin, Christelle, Loaëc, Nadège, Birling, Marie-Christine, Selloum, Mohammed, Normand, Elisabeth, Pavlovic, Guillaume, Sorg, Tania, Stunnenberg, Henk G, Chelly, Jamel, Humeau, Yann, Friocourt, Gaëlle, Hérault, Yann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985730/ https://www.ncbi.nlm.nih.gov/pubmed/29659809 http://dx.doi.org/10.1093/hmg/ddy122

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