Memantine induces manic episode in a 73-year-old patient with vascular neurocognitive disorder: a case report

Memantine, an N-methyl-d-aspartate receptor antagonist, is a well-established treatment option for moderate-to-severe cognitive impairment related to Alzheimer disease. Recently, growing evidence has indicated memantine might also be effective in treatment of affective disorders. The common drug-ind...

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Autores principales: Duan, Jinfeng, Lao, Chengming, Chen, Jingkai, Pan, Fen, Zhang, Chenlin, Xu, Weijuan, Zhou, Weihua, Hu, Jianbo, Shang, Desheng, Huang, Manli, Xu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985765/
https://www.ncbi.nlm.nih.gov/pubmed/29881276
http://dx.doi.org/10.2147/NDT.S160832
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author Duan, Jinfeng
Lao, Chengming
Chen, Jingkai
Pan, Fen
Zhang, Chenlin
Xu, Weijuan
Zhou, Weihua
Hu, Jianbo
Shang, Desheng
Huang, Manli
Xu, Yi
author_facet Duan, Jinfeng
Lao, Chengming
Chen, Jingkai
Pan, Fen
Zhang, Chenlin
Xu, Weijuan
Zhou, Weihua
Hu, Jianbo
Shang, Desheng
Huang, Manli
Xu, Yi
author_sort Duan, Jinfeng
collection PubMed
description Memantine, an N-methyl-d-aspartate receptor antagonist, is a well-established treatment option for moderate-to-severe cognitive impairment related to Alzheimer disease. Recently, growing evidence has indicated memantine might also be effective in treatment of affective disorders. The common drug-induced adverse events of memantine include confusion, dizziness, drowsiness, headache, insomnia, and agitation. Herein, we presented a case of a 73-year-old female patient with vascular neurocognitive disorder, who developed a manic episode after taking memantine.
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spelling pubmed-59857652018-06-07 Memantine induces manic episode in a 73-year-old patient with vascular neurocognitive disorder: a case report Duan, Jinfeng Lao, Chengming Chen, Jingkai Pan, Fen Zhang, Chenlin Xu, Weijuan Zhou, Weihua Hu, Jianbo Shang, Desheng Huang, Manli Xu, Yi Neuropsychiatr Dis Treat Case Report Memantine, an N-methyl-d-aspartate receptor antagonist, is a well-established treatment option for moderate-to-severe cognitive impairment related to Alzheimer disease. Recently, growing evidence has indicated memantine might also be effective in treatment of affective disorders. The common drug-induced adverse events of memantine include confusion, dizziness, drowsiness, headache, insomnia, and agitation. Herein, we presented a case of a 73-year-old female patient with vascular neurocognitive disorder, who developed a manic episode after taking memantine. Dove Medical Press 2018-05-30 /pmc/articles/PMC5985765/ /pubmed/29881276 http://dx.doi.org/10.2147/NDT.S160832 Text en © 2018 Duan et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Case Report
Duan, Jinfeng
Lao, Chengming
Chen, Jingkai
Pan, Fen
Zhang, Chenlin
Xu, Weijuan
Zhou, Weihua
Hu, Jianbo
Shang, Desheng
Huang, Manli
Xu, Yi
Memantine induces manic episode in a 73-year-old patient with vascular neurocognitive disorder: a case report
title Memantine induces manic episode in a 73-year-old patient with vascular neurocognitive disorder: a case report
title_full Memantine induces manic episode in a 73-year-old patient with vascular neurocognitive disorder: a case report
title_fullStr Memantine induces manic episode in a 73-year-old patient with vascular neurocognitive disorder: a case report
title_full_unstemmed Memantine induces manic episode in a 73-year-old patient with vascular neurocognitive disorder: a case report
title_short Memantine induces manic episode in a 73-year-old patient with vascular neurocognitive disorder: a case report
title_sort memantine induces manic episode in a 73-year-old patient with vascular neurocognitive disorder: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985765/
https://www.ncbi.nlm.nih.gov/pubmed/29881276
http://dx.doi.org/10.2147/NDT.S160832
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