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Cholesteryl oleate-loaded cationic solid lipid nanoparticles as carriers for efficient gene-silencing therapy
BACKGROUND: Cationic solid lipid nanoparticles (SLNs) have been given considerable attention for therapeutic nucleic acid delivery owing to their advantages over viral and other nanoparticle delivery systems. However, poor delivery efficiency and complex formulations hinder the clinical translation...
Autores principales: | Suñé-Pou, Marc, Prieto-Sánchez, Silvia, El Yousfi, Younes, Boyero-Corral, Sofía, Nardi-Ricart, Anna, Nofrerias-Roig, Isaac, Pérez-Lozano, Pilar, García-Montoya, Encarna, Miñarro-Carmona, Montserrat, Ticó, Josep Ramón, Suñé-Negre, Josep Mª, Hernández-Munain, Cristina, Suñé, Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985802/ https://www.ncbi.nlm.nih.gov/pubmed/29881274 http://dx.doi.org/10.2147/IJN.S158884 |
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