Mesalamine Associated Bradycardia

A 38-year-old female presented with an acute flare of ulcerative colitis. She was started on prednisone and mesalamine. Within 24 hours of initiating mesalamine, she developed sinus bradycardia. After holding mesalamine, the heart rate returned to normal within five days. Our case illustrates the th...

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Detalles Bibliográficos
Autores principales: Krzyzak, Michael, Gupta, Anupam, Antonov, Evgeny, Mulrooney, Stephen M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985920/
https://www.ncbi.nlm.nih.gov/pubmed/29872605
http://dx.doi.org/10.7759/cureus.2425
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author Krzyzak, Michael
Gupta, Anupam
Antonov, Evgeny
Mulrooney, Stephen M
author_facet Krzyzak, Michael
Gupta, Anupam
Antonov, Evgeny
Mulrooney, Stephen M
author_sort Krzyzak, Michael
collection PubMed
description A 38-year-old female presented with an acute flare of ulcerative colitis. She was started on prednisone and mesalamine. Within 24 hours of initiating mesalamine, she developed sinus bradycardia. After holding mesalamine, the heart rate returned to normal within five days. Our case illustrates the third described case, to our knowledge, of severe sinus bradycardia secondary to mesalamine.
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spelling pubmed-59859202018-06-05 Mesalamine Associated Bradycardia Krzyzak, Michael Gupta, Anupam Antonov, Evgeny Mulrooney, Stephen M Cureus Internal Medicine A 38-year-old female presented with an acute flare of ulcerative colitis. She was started on prednisone and mesalamine. Within 24 hours of initiating mesalamine, she developed sinus bradycardia. After holding mesalamine, the heart rate returned to normal within five days. Our case illustrates the third described case, to our knowledge, of severe sinus bradycardia secondary to mesalamine. Cureus 2018-04-04 /pmc/articles/PMC5985920/ /pubmed/29872605 http://dx.doi.org/10.7759/cureus.2425 Text en Copyright © 2018, Krzyzak et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Krzyzak, Michael
Gupta, Anupam
Antonov, Evgeny
Mulrooney, Stephen M
Mesalamine Associated Bradycardia
title Mesalamine Associated Bradycardia
title_full Mesalamine Associated Bradycardia
title_fullStr Mesalamine Associated Bradycardia
title_full_unstemmed Mesalamine Associated Bradycardia
title_short Mesalamine Associated Bradycardia
title_sort mesalamine associated bradycardia
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985920/
https://www.ncbi.nlm.nih.gov/pubmed/29872605
http://dx.doi.org/10.7759/cureus.2425
work_keys_str_mv AT krzyzakmichael mesalamineassociatedbradycardia
AT guptaanupam mesalamineassociatedbradycardia
AT antonovevgeny mesalamineassociatedbradycardia
AT mulrooneystephenm mesalamineassociatedbradycardia

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