Fatal massive hemolysis caused by immunoglobulin M anti‐c antibody in a patient with newly diagnosed B‐cell acute lymphoblastic leukemia: a case report

Delayed hemolytic transfusion reactions (DHTRs) occur secondary to slow, mild IgG‐mediated processes against minor red blood cell antigens. Herein, we report the case of a rapidly fatal alloimmune anti‐c IgM‐mediated hemolysis, a rare, previously undescribed, pathophysiologic scenario. Early recogni...

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Detalles Bibliográficos
Autores principales: Galvez, Carlos, Abutaleb, Abdulrahman, Iams, Wade T., Lindholm, Paul F., Kwaan, Hau C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986000/
https://www.ncbi.nlm.nih.gov/pubmed/29881571
http://dx.doi.org/10.1002/ccr3.1534
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author Galvez, Carlos
Abutaleb, Abdulrahman
Iams, Wade T.
Lindholm, Paul F.
Kwaan, Hau C.
author_facet Galvez, Carlos
Abutaleb, Abdulrahman
Iams, Wade T.
Lindholm, Paul F.
Kwaan, Hau C.
author_sort Galvez, Carlos
collection PubMed
description Delayed hemolytic transfusion reactions (DHTRs) occur secondary to slow, mild IgG‐mediated processes against minor red blood cell antigens. Herein, we report the case of a rapidly fatal alloimmune anti‐c IgM‐mediated hemolysis, a rare, previously undescribed, pathophysiologic scenario. Early recognition of such phenomena can expedite supportive measures and optimize patient outcomes.
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spelling pubmed-59860002018-06-07 Fatal massive hemolysis caused by immunoglobulin M anti‐c antibody in a patient with newly diagnosed B‐cell acute lymphoblastic leukemia: a case report Galvez, Carlos Abutaleb, Abdulrahman Iams, Wade T. Lindholm, Paul F. Kwaan, Hau C. Clin Case Rep Case Reports Delayed hemolytic transfusion reactions (DHTRs) occur secondary to slow, mild IgG‐mediated processes against minor red blood cell antigens. Herein, we report the case of a rapidly fatal alloimmune anti‐c IgM‐mediated hemolysis, a rare, previously undescribed, pathophysiologic scenario. Early recognition of such phenomena can expedite supportive measures and optimize patient outcomes. John Wiley and Sons Inc. 2018-04-17 /pmc/articles/PMC5986000/ /pubmed/29881571 http://dx.doi.org/10.1002/ccr3.1534 Text en © 2018 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Galvez, Carlos
Abutaleb, Abdulrahman
Iams, Wade T.
Lindholm, Paul F.
Kwaan, Hau C.
Fatal massive hemolysis caused by immunoglobulin M anti‐c antibody in a patient with newly diagnosed B‐cell acute lymphoblastic leukemia: a case report
title Fatal massive hemolysis caused by immunoglobulin M anti‐c antibody in a patient with newly diagnosed B‐cell acute lymphoblastic leukemia: a case report
title_full Fatal massive hemolysis caused by immunoglobulin M anti‐c antibody in a patient with newly diagnosed B‐cell acute lymphoblastic leukemia: a case report
title_fullStr Fatal massive hemolysis caused by immunoglobulin M anti‐c antibody in a patient with newly diagnosed B‐cell acute lymphoblastic leukemia: a case report
title_full_unstemmed Fatal massive hemolysis caused by immunoglobulin M anti‐c antibody in a patient with newly diagnosed B‐cell acute lymphoblastic leukemia: a case report
title_short Fatal massive hemolysis caused by immunoglobulin M anti‐c antibody in a patient with newly diagnosed B‐cell acute lymphoblastic leukemia: a case report
title_sort fatal massive hemolysis caused by immunoglobulin m anti‐c antibody in a patient with newly diagnosed b‐cell acute lymphoblastic leukemia: a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986000/
https://www.ncbi.nlm.nih.gov/pubmed/29881571
http://dx.doi.org/10.1002/ccr3.1534
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