Cyclic compressive loading activates angiotensin II type 1 receptor in articular chondrocytes and stimulates hypertrophic differentiation through a G‐protein‐dependent pathway

Angiotensin II type 1 receptor (AT1R) appears to have a mechanosensing function in a number of cell types. The purpose of this study was to examine whether AT1R expressed in articular chondrocytes is involved in osteoarthritis (OA) progression in vivo and whether cyclic compressive loading activates...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakamura, Fumihisa, Tsukamoto, Ichiro, Inoue, Shinji, Hashimoto, Kazuhiko, Akagi, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986009/
https://www.ncbi.nlm.nih.gov/pubmed/29928576
http://dx.doi.org/10.1002/2211-5463.12438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986009/
https://www.ncbi.nlm.nih.gov/pubmed/29928576
http://dx.doi.org/10.1002/2211-5463.12438

Ejemplares similares