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Polymeric glabrescione B nanocapsules for passive targeting of Hedgehog-dependent tumor therapy in vitro
AIM: With the purpose of delivering high doses of glabrescione B (GlaB) to solid tumors after systemic administration, long-circulating GlaB-loaded oil-cored polymeric nanocapsules (NC-GlaB) were formulated. MATERIALS & METHODS: Synthesis of GlaB and its encapsulation in nanocapsules (NCs) was p...
Autores principales: | Ingallina, Cinzia, Costa, Pedro M, Ghirga, Francesca, Klippstein, Rebecca, Wang, Julie T, Berardozzi, Simone, Hodgins, Naomi, Infante, Paola, Pollard, Steven M, Botta, Bruno, Al-Jamal, Khuloud T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Medicine Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986025/ https://www.ncbi.nlm.nih.gov/pubmed/28322108 http://dx.doi.org/10.2217/nnm-2016-0388 |
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