Enhanced vulnerability to oxidative stress and induction of inflammatory gene expression in 3‐phosphoglycerate dehydrogenase‐deficient fibroblasts

l‐Serine (l‐Ser) is a necessary precursor for the synthesis of proteins, lipids, glycine, cysteine, d‐serine, and tetrahydrofolate metabolites. Low l‐Ser availability activates stress responses and cell death; however, the underlying molecular mechanisms remain unclear. l‐Ser is synthesized de novo...

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Detalles Bibliográficos
Autores principales: Hamano, Momoko, Haraguchi, Yurina, Sayano, Tomoko, Zyao, Chong, Arimoto, Yashiho, Kawano, Yui, Moriyasu, Kazuki, Udono, Miyako, Katakura, Yoshinori, Ogawa, Takuya, Kato, Hisanori, Furuya, Shigeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986034/
https://www.ncbi.nlm.nih.gov/pubmed/29928571
http://dx.doi.org/10.1002/2211-5463.12429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986034/
https://www.ncbi.nlm.nih.gov/pubmed/29928571
http://dx.doi.org/10.1002/2211-5463.12429

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