Leukemic mature B‐cell neoplasm observed during the treatment with romiplostim in patient with thrombocytopenia and liver cirrhosis

We report here a new adverse event of romiplostim which is a protein analog of thrombopoietin. Leukemic mature B‐cell neoplasm was observed during the treatment of thrombocytopenia in a patient with liver cirrhosis. Their relationship was suggested clinically but the mechanism of leukemic expansion...

Descripción completa

Detalles Bibliográficos
Autores principales: Osawa, Marina, Akiyama, Hideki, Mae, Sunao, Fujiwara, Yuko, Yamane, Michio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986044/
https://www.ncbi.nlm.nih.gov/pubmed/29881570
http://dx.doi.org/10.1002/ccr3.1530
_version_ 1783328865251229696
author Osawa, Marina
Akiyama, Hideki
Mae, Sunao
Fujiwara, Yuko
Yamane, Michio
author_facet Osawa, Marina
Akiyama, Hideki
Mae, Sunao
Fujiwara, Yuko
Yamane, Michio
author_sort Osawa, Marina
collection PubMed
description We report here a new adverse event of romiplostim which is a protein analog of thrombopoietin. Leukemic mature B‐cell neoplasm was observed during the treatment of thrombocytopenia in a patient with liver cirrhosis. Their relationship was suggested clinically but the mechanism of leukemic expansion of lymphoma cells was not clarified.
format Online
Article
Text
id pubmed-5986044
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-59860442018-06-07 Leukemic mature B‐cell neoplasm observed during the treatment with romiplostim in patient with thrombocytopenia and liver cirrhosis Osawa, Marina Akiyama, Hideki Mae, Sunao Fujiwara, Yuko Yamane, Michio Clin Case Rep Case Reports We report here a new adverse event of romiplostim which is a protein analog of thrombopoietin. Leukemic mature B‐cell neoplasm was observed during the treatment of thrombocytopenia in a patient with liver cirrhosis. Their relationship was suggested clinically but the mechanism of leukemic expansion of lymphoma cells was not clarified. John Wiley and Sons Inc. 2018-04-17 /pmc/articles/PMC5986044/ /pubmed/29881570 http://dx.doi.org/10.1002/ccr3.1530 Text en © 2018 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Osawa, Marina
Akiyama, Hideki
Mae, Sunao
Fujiwara, Yuko
Yamane, Michio
Leukemic mature B‐cell neoplasm observed during the treatment with romiplostim in patient with thrombocytopenia and liver cirrhosis
title Leukemic mature B‐cell neoplasm observed during the treatment with romiplostim in patient with thrombocytopenia and liver cirrhosis
title_full Leukemic mature B‐cell neoplasm observed during the treatment with romiplostim in patient with thrombocytopenia and liver cirrhosis
title_fullStr Leukemic mature B‐cell neoplasm observed during the treatment with romiplostim in patient with thrombocytopenia and liver cirrhosis
title_full_unstemmed Leukemic mature B‐cell neoplasm observed during the treatment with romiplostim in patient with thrombocytopenia and liver cirrhosis
title_short Leukemic mature B‐cell neoplasm observed during the treatment with romiplostim in patient with thrombocytopenia and liver cirrhosis
title_sort leukemic mature b‐cell neoplasm observed during the treatment with romiplostim in patient with thrombocytopenia and liver cirrhosis
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986044/
https://www.ncbi.nlm.nih.gov/pubmed/29881570
http://dx.doi.org/10.1002/ccr3.1530
work_keys_str_mv AT osawamarina leukemicmaturebcellneoplasmobservedduringthetreatmentwithromiplostiminpatientwiththrombocytopeniaandlivercirrhosis
AT akiyamahideki leukemicmaturebcellneoplasmobservedduringthetreatmentwithromiplostiminpatientwiththrombocytopeniaandlivercirrhosis
AT maesunao leukemicmaturebcellneoplasmobservedduringthetreatmentwithromiplostiminpatientwiththrombocytopeniaandlivercirrhosis
AT fujiwarayuko leukemicmaturebcellneoplasmobservedduringthetreatmentwithromiplostiminpatientwiththrombocytopeniaandlivercirrhosis
AT yamanemichio leukemicmaturebcellneoplasmobservedduringthetreatmentwithromiplostiminpatientwiththrombocytopeniaandlivercirrhosis

Ejemplares similares