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Hematopoietic cell transplantation for myeloid/NK cell precursor acute leukemia in second remission

Myeloid/natural killer cell precursor acute leukemia (MNKPL) is a rare leukemia subtype characterized by a high incidence of extramedullary infiltration. No appropriate treatment strategy has so far been developed. Acute myelogenous leukemia‐type chemotherapy combined with L‐Asparaginase is an effec...

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Detalles Bibliográficos
Autores principales: Noguchi, Yusuke, Tomizawa, Daisuke, Hiroki, Haruka, Miyamoto, Satoshi, Tezuka, Mari, Miyawaki, Reiji, Tanaka‐Kubota, Mari, Okano, Tubasa, Kobayashi, Chika, Mitsuiki, Noriko, Aoki, Yuki, Imai, Kohsuke, Kajiwara, Michiko, Kanegane, Hirokazu, Morio, Tomohiro, Takagi, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986054/
https://www.ncbi.nlm.nih.gov/pubmed/29881556
http://dx.doi.org/10.1002/ccr3.1506
Descripción
Sumario:Myeloid/natural killer cell precursor acute leukemia (MNKPL) is a rare leukemia subtype characterized by a high incidence of extramedullary infiltration. No appropriate treatment strategy has so far been developed. Acute myelogenous leukemia‐type chemotherapy combined with L‐Asparaginase is an effective treatment for MNKPL. Hematopoietic cell transplantation is a second option in refractory cases.