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An information theoretic framework reveals a tunable allosteric network in group II chaperonins

The ATP-dependent allosteric regulation of the ring-shaped Group II chaperonins remains ill-defined. Their complex oligomeric topology limited the success of structural techniques in suggesting allosteric determinants. Further, their high sequence conservation has hindered prediction of allosteric n...

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Detalles Bibliográficos
Autores principales: Lopez, Tom, Dalton, Kevin, Tomlinson, Anthony, Pande, Vijay, Frydman, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986071/
https://www.ncbi.nlm.nih.gov/pubmed/28741612
http://dx.doi.org/10.1038/nsmb.3440

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