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An information theoretic framework reveals a tunable allosteric network in group II chaperonins
The ATP-dependent allosteric regulation of the ring-shaped Group II chaperonins remains ill-defined. Their complex oligomeric topology limited the success of structural techniques in suggesting allosteric determinants. Further, their high sequence conservation has hindered prediction of allosteric n...
Autores principales: | Lopez, Tom, Dalton, Kevin, Tomlinson, Anthony, Pande, Vijay, Frydman, Judith |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986071/ https://www.ncbi.nlm.nih.gov/pubmed/28741612 http://dx.doi.org/10.1038/nsmb.3440 |
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