Insight into the substrate specificity change caused by the Y227H mutation of α-glucosidase III from the European honeybee (Apis mellifera) through molecular dynamics simulations

Honey from the European honeybee, Apis mellifera, is produced by α-glucosidases (HBGases) and is widely used in food, pharmaceutical, and cosmetic industries. Categorized by their substrate specificities, HBGases have three isoforms: HBGase I, II and III. Previous experimental investigations showed...

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Detalles Bibliográficos
Autores principales: Na Ayutthaya, Pratchaya Pramoj, Chanchao, Chanpen, Chunsrivirot, Surasak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986129/
https://www.ncbi.nlm.nih.gov/pubmed/29864156
http://dx.doi.org/10.1371/journal.pone.0198484

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