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Impact of OGT deregulation on EZH2 target genes FOXA1 and FOXC1 expression in breast cancer cells
Enhancer of zest homolog 2 (EZH2) is a histone methyltransferase which plays a crucial role in cancer progression by regulation of genes involved in cellular processes such as proliferation, invasion and self-renewal. Activity and biological function of EZH2 are regulated by posttranslational modifi...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986130/ https://www.ncbi.nlm.nih.gov/pubmed/29864144 http://dx.doi.org/10.1371/journal.pone.0198351 |