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Intestinal mucin activates human dendritic cells and IL-8 production in a glycan-specific manner
Cross-talk between different components of the intestinal barrier and the immune system may be important in maintaining gut homeostasis. A crucial part of the gut barrier is the mucus layer, a cross-linked gel on top of the intestinal epithelium that consists predominantly of the mucin glycoprotein...
Autores principales: | Melo-Gonzalez, Felipe, Fenton, Thomas M., Forss, Cecilia, Smedley, Catherine, Goenka, Anu, MacDonald, Andrew S., Thornton, David J., Travis, Mark A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986209/ https://www.ncbi.nlm.nih.gov/pubmed/29581231 http://dx.doi.org/10.1074/jbc.M117.789305 |
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