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Reduced expression of C/EBPβ-LIP extends health and lifespan in mice
Ageing is associated with physical decline and the development of age-related diseases such as metabolic disorders and cancer. Few conditions are known that attenuate the adverse effects of ageing, including calorie restriction (CR) and reduced signalling through the mechanistic target of rapamycin...
Autores principales: | Müller, Christine, Zidek, Laura M, Ackermann, Tobias, de Jong, Tristan, Liu, Peng, Kliche, Verena, Zaini, Mohamad Amr, Kortman, Gertrud, Harkema, Liesbeth, Verbeek, Dineke S, Tuckermann, Jan P, von Maltzahn, Julia, de Bruin, Alain, Guryev, Victor, Wang, Zhao-Qi, Calkhoven, Cornelis F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986274/ https://www.ncbi.nlm.nih.gov/pubmed/29708496 http://dx.doi.org/10.7554/eLife.34985 |
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