Cargando…

KUS121, an ATP regulator, mitigates chorioretinal pathologies in animal models of age-related macular degeneration

Age-related macular degeneration (AMD) is a leading cause of blindness among elderly people. The appearance of drusen is a clinical manifestation and a harbinger of both exudative and atrophic AMD. Recently, antibody-based medicines have been used to treat the exudative type. However, they do not re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Muraoka, Yuki, Iida, Yuto, Ikeda, Hanako O., Iwai, Sachiko, Hata, Masayuki, Iwata, Takeshi, Nakayama, Mao, Shimozawa, Nobuhiro, Katakai, Yuko, Kakizuka, Akira, Yoshimura, Nagahisa, Tsujikawa, Akitaka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986307/ https://www.ncbi.nlm.nih.gov/pubmed/29872758 http://dx.doi.org/10.1016/j.heliyon.2018.e00624

Ejemplares similares

KUS121 attenuates the progression of monosodium iodoacetate-induced osteoarthritis in rats
por: Iwai, Sachiko, et al.
Publicado: (2021)

KUS121, a VCP modulator, attenuates ischemic retinal cell death via suppressing endoplasmic reticulum stress
por: Hata, Masayuki, et al.
Publicado: (2017)

Neuoroprotective efficacies by KUS121, a VCP modulator, on animal models of retinal degeneration
por: Hasegawa, Tomoko, et al.
Publicado: (2016)

Safety and effectiveness of a novel neuroprotectant, KUS121, in patients with non-arteritic central retinal artery occlusion: An open-label, non-randomized, first-in-humans, phase 1/2 trial
por: Ikeda, Hanako Ohashi, et al.
Publicado: (2020)

A VCP modulator, KUS121, as a promising therapeutic agent for post-traumatic osteoarthritis
por: Saito, Motoo, et al.
Publicado: (2020)

KUS121, a valosin-containing protein modulator, attenuates ischemic stroke via preventing ATP depletion
por: Kinoshita, Hisanori, et al.
Publicado: (2019)

Author Correction: A VCP modulator, KUS121, as a promising therapeutic agent for post-traumatic osteoarthritis
por: Saito, Motoo, et al.
Publicado: (2021)

Cardioprotective Effects of VCP Modulator KUS121 in Murine and Porcine Models of Myocardial Infarction
por: Ide, Yuya, et al.
Publicado: (2019)

Branched Chain Amino Acids Promote ATP Production Via Translocation of Glucose Transporters
por: Iwai, Sachiko, et al.
Publicado: (2022)

Effect of VCP modulators on gene expression profiles of retinal ganglion cells in an acute injury mouse model
por: Hasegawa, Tomoko, et al.
Publicado: (2020)

Hop flower extracts mitigate retinal ganglion cell degeneration in a glaucoma mouse model
por: Hasegawa, Tomoko, et al.
Publicado: (2020)

Reduction of lipid accumulation rescues Bietti’s crystalline dystrophy phenotypes
por: Hata, Masayuki, et al.
Publicado: (2018)

Branched chain amino acids attenuate major pathologies in mouse models of retinal degeneration and glaucoma
por: Hasegawa, Tomoko, et al.
Publicado: (2018)

Association between retinal hemorrhagic pattern and macular perfusion status in eyes with acute branch retinal vein occlusion
por: Muraoka, Yuki, et al.
Publicado: (2016)

De Kus /
por: Gershten, Donna M.
Publicado: (2002)

Foveal Damage Due to Subfoveal Hemorrhage Associated with Branch Retinal Vein Occlusion
por: Muraoka, Yuki, et al.
Publicado: (2015)

Modulation of valosin-containing protein by Kyoto University Substances (KUS) as a novel therapeutic strategy for ischemic neuronal diseases
por: Hata, Masayuki, et al.
Publicado: (2017)

Neuroprotective effects of VCP modulators in mouse models of glaucoma
por: Nakano, Noriko, et al.
Publicado: (2016)

Grid photocoagulation combined with intravitreal bevacizumab for recurrent macular edema associated with retinal vein occlusion
por: Ogino, Ken, et al.
Publicado: (2011)

Involvement of endothelins in neuroprotection of valosin-containing protein modulators against retinal ganglion cell damage
por: Kusaka, Mami, et al.
Publicado: (2022)

Novel VCP modulators mitigate major pathologies of rd10, a mouse model of retinitis pigmentosa
por: Ikeda, Hanako Ohashi, et al.
Publicado: (2014)

Branch Retinal Vein Occlusion: Treatment Outcomes According to the Retinal Nonperfusion Area, Clinical Subtype, and Crossing Pattern
por: Iida-Miwa, Yuko, et al.
Publicado: (2019)

Peripheral Chorioretinal Imaging Through a Front Prism on Optical Coherence Tomography Angiography
por: Kawai, Kentaro, et al.
Publicado: (2021)

Subfoveal serous retinal detachment associated with extramacular branch retinal vein occlusion
por: Ota, Toru, et al.
Publicado: (2013)

Real-Time Imaging of Rabbit Retina with Retinal Degeneration by Using Spectral-Domain Optical Coherence Tomography
por: Muraoka, Yuki, et al.
Publicado: (2012)

Unilateral transient high myopization after pediatric strabismus surgery: Observation by anterior segment optical coherence tomography
por: Yoshimura, Akihito, et al.
Publicado: (2022)

Characteristics of pachychoroid neovasculopathy
por: Tagawa, Miho, et al.
Publicado: (2020)

Choroidal thickness after intravitreal ranibizumab injections for choroidal neovascularization
por: Ellabban, Abdallah A, et al.
Publicado: (2012)

Analysis of Fundus Shape in Highly Myopic Eyes by Using Curvature Maps Constructed from Optical Coherence Tomography
por: Miyake, Masahiro, et al.
Publicado: (2014)

Evaluation of the Efficiency and Safety of a 27-Gauge 20,000 Cuts per Minute Vitreous Cutter
por: Doi, Yuta, et al.
Publicado: (2023)

Coccidioidomycosis Chorioretinitis
por: Nordstrom, Brian, et al.
Publicado: (2019)

The chorioretinal “blast”
por: Akhila, M, et al.
Publicado: (2020)

Effects of Intravitreous Aflibercept Injection in Pachychoroid Neovasculopathy: Comparison with Typical Neovascular Age-Related Macular Degeneration
por: Elfandi, Sufian, et al.
Publicado: (2021)

Angiographic Risk Features of Branch Retinal Vein Occlusion Onset as Determined by Optical Coherence Tomography Angiography
por: Kogo, Takahiro, et al.
Publicado: (2020)

Primary Tubercular Chorioretinitis
por: Akal, A, et al.
Publicado: (2014)

Ultra-widefield confocal imaging of multiple evanescent white dot syndrome
por: Kadomoto, Shin, et al.
Publicado: (2020)

High-contrast scleroconjunctival microvasculature via deep learning denoising
por: Kadomoto, Shin, et al.
Publicado: (2020)

Macular retinal circulation in healthy eyes examined by optical coherence tomography angiography extended interscan time analysis
por: Ishikura, Masaharu, et al.
Publicado: (2023)

Retinal Blood Flow Velocity Change in Parafoveal Capillary after Topical Tafluprost Treatment in Eyes with Primary Open-angle Glaucoma
por: Iida, Yuto, et al.
Publicado: (2017)

A novel clinical sign in intraocular tuberculosis: Active chorioretinitis within chorioretinal atrophy
por: Pathengay, Avinash, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_qrgupk3j0mjkeslv1bh1obg06p