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Maternal DHA Status during Pregnancy Has a Positive Impact on Infant Problem Solving: A Norwegian Prospective Observation Study

Docosahexaenoic acid (DHA, 22:6, n-3) is a long-chain polyunsaturated fatty acid necessary for normal brain growth and cognitive development. Seafood and dietary supplements are the primary dietary sources of DHA. This study addresses the associations between DHA status in pregnant women and healthy...

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Autores principales: Braarud, Hanne Cecilie, Markhus, Maria Wik, Skotheim, Siv, Stormark, Kjell Morten, Frøyland, Livar, Graff, Ingvild Eide, Kjellevold, Marian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986409/
https://www.ncbi.nlm.nih.gov/pubmed/29695097
http://dx.doi.org/10.3390/nu10050529
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author Braarud, Hanne Cecilie
Markhus, Maria Wik
Skotheim, Siv
Stormark, Kjell Morten
Frøyland, Livar
Graff, Ingvild Eide
Kjellevold, Marian
author_facet Braarud, Hanne Cecilie
Markhus, Maria Wik
Skotheim, Siv
Stormark, Kjell Morten
Frøyland, Livar
Graff, Ingvild Eide
Kjellevold, Marian
author_sort Braarud, Hanne Cecilie
collection PubMed
description Docosahexaenoic acid (DHA, 22:6, n-3) is a long-chain polyunsaturated fatty acid necessary for normal brain growth and cognitive development. Seafood and dietary supplements are the primary dietary sources of DHA. This study addresses the associations between DHA status in pregnant women and healthy, term-born infant problem-solving skills assessed using the Ages and Stages Questionnaire. The fatty acid status of maternal red blood cells (RBCs) was assessed in the 28th week of gestation and at three months postpartum. The infants’ fatty acid status (RBC) was assessed at three, six, and twelve months, and problem-solving skills were assessed at six and twelve months. Maternal DHA status in pregnancy was found to be positively associated with infants’ problem-solving skills at 12 months. This association remained significant even after controlling for the level of maternal education, a surrogate for socio-economic status. The infants’ DHA status at three months was associated with the infants’ problem solving at 12 months. The results accentuate the importance for pregnant and lactating women to have a satisfactory DHA status from dietary intake of seafood or other sources rich in DHA.
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spelling pubmed-59864092018-06-05 Maternal DHA Status during Pregnancy Has a Positive Impact on Infant Problem Solving: A Norwegian Prospective Observation Study Braarud, Hanne Cecilie Markhus, Maria Wik Skotheim, Siv Stormark, Kjell Morten Frøyland, Livar Graff, Ingvild Eide Kjellevold, Marian Nutrients Article Docosahexaenoic acid (DHA, 22:6, n-3) is a long-chain polyunsaturated fatty acid necessary for normal brain growth and cognitive development. Seafood and dietary supplements are the primary dietary sources of DHA. This study addresses the associations between DHA status in pregnant women and healthy, term-born infant problem-solving skills assessed using the Ages and Stages Questionnaire. The fatty acid status of maternal red blood cells (RBCs) was assessed in the 28th week of gestation and at three months postpartum. The infants’ fatty acid status (RBC) was assessed at three, six, and twelve months, and problem-solving skills were assessed at six and twelve months. Maternal DHA status in pregnancy was found to be positively associated with infants’ problem-solving skills at 12 months. This association remained significant even after controlling for the level of maternal education, a surrogate for socio-economic status. The infants’ DHA status at three months was associated with the infants’ problem solving at 12 months. The results accentuate the importance for pregnant and lactating women to have a satisfactory DHA status from dietary intake of seafood or other sources rich in DHA. MDPI 2018-04-24 /pmc/articles/PMC5986409/ /pubmed/29695097 http://dx.doi.org/10.3390/nu10050529 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Braarud, Hanne Cecilie
Markhus, Maria Wik
Skotheim, Siv
Stormark, Kjell Morten
Frøyland, Livar
Graff, Ingvild Eide
Kjellevold, Marian
Maternal DHA Status during Pregnancy Has a Positive Impact on Infant Problem Solving: A Norwegian Prospective Observation Study
title Maternal DHA Status during Pregnancy Has a Positive Impact on Infant Problem Solving: A Norwegian Prospective Observation Study
title_full Maternal DHA Status during Pregnancy Has a Positive Impact on Infant Problem Solving: A Norwegian Prospective Observation Study
title_fullStr Maternal DHA Status during Pregnancy Has a Positive Impact on Infant Problem Solving: A Norwegian Prospective Observation Study
title_full_unstemmed Maternal DHA Status during Pregnancy Has a Positive Impact on Infant Problem Solving: A Norwegian Prospective Observation Study
title_short Maternal DHA Status during Pregnancy Has a Positive Impact on Infant Problem Solving: A Norwegian Prospective Observation Study
title_sort maternal dha status during pregnancy has a positive impact on infant problem solving: a norwegian prospective observation study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986409/
https://www.ncbi.nlm.nih.gov/pubmed/29695097
http://dx.doi.org/10.3390/nu10050529
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