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Elucidation of the critical epitope of an anti-EGFR monoclonal antibody EMab-134
The epidermal growth factor receptor (EGFR) is a type-1 transmembrane receptor tyrosine kinase, which activates the downstream signaling cascades in many tumors, such as oral and lung cancers. We previously developed EMab-134, a novel anti-EGFR monoclonal antibody (mAb), which reacts with endogenous...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986659/ https://www.ncbi.nlm.nih.gov/pubmed/29872734 http://dx.doi.org/10.1016/j.bbrep.2018.03.010 |