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Elucidation of the critical epitope of an anti-EGFR monoclonal antibody EMab-134

The epidermal growth factor receptor (EGFR) is a type-1 transmembrane receptor tyrosine kinase, which activates the downstream signaling cascades in many tumors, such as oral and lung cancers. We previously developed EMab-134, a novel anti-EGFR monoclonal antibody (mAb), which reacts with endogenous...

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Detalles Bibliográficos
Autores principales:	Kaneko, Mika K., Yamada, Shinji, Itai, Shunsuke, Chang, Yao-Wen, Nakamura, Takuro, Yanaka, Miyuki, Kato, Yukinari
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986659/ https://www.ncbi.nlm.nih.gov/pubmed/29872734 http://dx.doi.org/10.1016/j.bbrep.2018.03.010

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