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DOCK9 induces membrane ruffles and Rac1 activity in cancer HeLa epithelial cells

Dedicator-of-cytokinesis (DOCK) proteins are a family of guanine-nucleotide exchange factors (GEF) for Rho GTPases. The DOCK-D homology subfamily comprises DOCK9, DOCK10, and DOCK11. DOCK9 and DOCK11 are GEFs for Cdc42 and induce filopodia, while DOCK10 is a dual GEF for Cdc42 and Rac1 and induces f...

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Detalles Bibliográficos
Autores principales:	Ruiz-Lafuente, Natalia, Minguela, Alfredo, Parrado, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986721/ https://www.ncbi.nlm.nih.gov/pubmed/29872750 http://dx.doi.org/10.1016/j.bbrep.2018.05.004

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