Activation of neutral sphingomyelinase 2 by starvation induces cell-protective autophagy via an increase in Golgi-localized ceramide

Autophagy is essential for optimal cell function and survival, and the entire process accompanies membrane dynamics. Ceramides are produced by different enzymes at different cellular membrane sites and mediate differential signaling. However, it remains unclear which ceramide-producing pathways/enzy...

Descripción completa

Detalles Bibliográficos
Autores principales: Back, Moon Jung, Ha, Hae Chan, Fu, Zhicheng, Choi, Jong Min, Piao, Yongwei, Won, Jong Hoon, Jang, Ji Min, Shin, In Chul, Kim, Dae Kyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986760/
https://www.ncbi.nlm.nih.gov/pubmed/29867196
http://dx.doi.org/10.1038/s41419-018-0709-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986760/
https://www.ncbi.nlm.nih.gov/pubmed/29867196
http://dx.doi.org/10.1038/s41419-018-0709-4

Ejemplares similares