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Activation of neutral sphingomyelinase 2 by starvation induces cell-protective autophagy via an increase in Golgi-localized ceramide
Autophagy is essential for optimal cell function and survival, and the entire process accompanies membrane dynamics. Ceramides are produced by different enzymes at different cellular membrane sites and mediate differential signaling. However, it remains unclear which ceramide-producing pathways/enzy...
Autores principales: | Back, Moon Jung, Ha, Hae Chan, Fu, Zhicheng, Choi, Jong Min, Piao, Yongwei, Won, Jong Hoon, Jang, Ji Min, Shin, In Chul, Kim, Dae Kyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986760/ https://www.ncbi.nlm.nih.gov/pubmed/29867196 http://dx.doi.org/10.1038/s41419-018-0709-4 |
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