The matrix proteins aggrecan and fibulin-1 play a key role in determining aortic stiffness

Stiffening of the aorta is an important independent risk factor for myocardial infarction and stroke. Yet its genetics is complex and little is known about its molecular drivers. We have identified for the first time, tagSNPs in the genes for extracellular matrix proteins, aggrecan and fibulin-1, th...

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Detalles Bibliográficos
Autores principales: Yasmin, Maskari, Raya Al, McEniery, Carmel M., Cleary, Sarah E., Li, Ye, Siew, Keith, Figg, Nichola L., Khir, Ashraf W., Cockcroft, John R., Wilkinson, Ian B., O’Shaughnessy, Kevin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986773/
https://www.ncbi.nlm.nih.gov/pubmed/29867203
http://dx.doi.org/10.1038/s41598-018-25851-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986773/
https://www.ncbi.nlm.nih.gov/pubmed/29867203
http://dx.doi.org/10.1038/s41598-018-25851-5

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