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Impairment of photoreceptor ribbon synapses in a novel Pomt1 conditional knockout mouse model of dystroglycanopathy

Hypoglycosylation of α-dystroglycan (α-DG) resulting from deficiency of protein O-mannosyltransferase 1 (POMT1) may cause severe neuromuscular dystrophies with brain and eye anomalies, named dystroglycanopathies. The retinal involvement of these disorders motivated us to generate a conditional knock...

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Detalles Bibliográficos
Autores principales:	Rubio-Fernández, Marcos, Uribe, Mary Luz, Vicente-Tejedor, Javier, Germain, Francisco, Susín-Lara, Cristina, Quereda, Cristina, Montoliu, Lluis, de la Villa, Pedro, Martín-Nieto, José, Cruces, Jesús
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986861/ https://www.ncbi.nlm.nih.gov/pubmed/29867208 http://dx.doi.org/10.1038/s41598-018-26855-x

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