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Artificial strain of human prions created in vitro
The molecular mechanism that determines under physiological conditions transmissibility of the most common human prion disease, sporadic Creutzfeldt-Jakob disease (sCJD) is unknown. We report the synthesis of new human prion from the recombinant human prion protein expressed in bacteria in reaction...
Autores principales: | Kim, Chae, Xiao, Xiangzhu, Chen, Shugui, Haldiman, Tracy, Smirnovas, Vitautas, Kofskey, Diane, Warren, Miriam, Surewicz, Krystyna, Maurer, Nicholas R., Kong, Qingzhong, Surewicz, Witold, Safar, Jiri G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986862/ https://www.ncbi.nlm.nih.gov/pubmed/29867164 http://dx.doi.org/10.1038/s41467-018-04584-z |
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