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Removing Background Co-occurrences of Transcription Factor Binding Sites Greatly Improves the Prediction of Specific Transcription Factor Cooperations

Today, it is well-known that in eukaryotic cells the complex interplay of transcription factors (TFs) bound to the DNA of promoters and enhancers is the basis for precise and specific control of transcription. Computational methods have been developed for the identification of potentially cooperatin...

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Detalles Bibliográficos
Autores principales: Meckbach, Cornelia, Wingender, Edgar, Gültas, Mehmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986914/
https://www.ncbi.nlm.nih.gov/pubmed/29896218
http://dx.doi.org/10.3389/fgene.2018.00189

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