Cargando…

Silencing amorpha-4,11-diene synthase Genes in Artemisia annua Leads to FPP Accumulation

Artemisia annua is established as an efficient crop for the production of the anti-malarial compound artemisinin, a sesquiterpene lactone synthesized and stored in Glandular Secretory Trichomes (GSTs) located on the leaves and inflorescences. Amorpha-4,11-diene synthase (AMS) catalyzes the conversio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Catania, Theresa M., Branigan, Caroline A., Stawniak, Natalia, Hodson, Jennifer, Harvey, David, Larson, Tony R., Czechowski, Tomasz, Graham, Ian A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Plant Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986941/ https://www.ncbi.nlm.nih.gov/pubmed/29896204 http://dx.doi.org/10.3389/fpls.2018.00547

Ejemplares similares

Isolation, characterization and structural studies of amorpha ― 4, 11diene synthase (ADS(3963)) from Artemisia annua L.
por: Alam, Pravej, et al.
Publicado: (2010)

Amorpha-4,11-diene synthase: a key enzyme in artemisinin biosynthesis and engineering
por: Huang, Jin Quan, et al.
Publicado: (2021)

Synthesis of amorpha-4,11-diene from dihydroartemisinic acid
por: Schwertz, Geoffrey, et al.
Publicado: (2019)

Catalysis of amorpha-4,11-diene synthase unraveled and improved by mutability landscape guided engineering
por: Abdallah, Ingy I., et al.
Publicado: (2018)

Correction to: Amorpha-4,11-diene synthase: a key enzyme in artemisinin biosynthesis and engineering
por: Huang, Jin Quan, et al.
Publicado: (2021)

Artemisia annua L. plants lacking Bornyl diPhosphate Synthase reallocate carbon from monoterpenes to sesquiterpenes except artemisinin
por: Czechowski, Tomasz, et al.
Publicado: (2022)

Detailed Phytochemical Analysis of High- and Low Artemisinin-Producing Chemotypes of Artemisia annua
por: Czechowski, Tomasz, et al.
Publicado: (2018)

Genetic analysis reveals the inconsistency of amorpha-4,11-diene synthase, a key enzyme in the artemisinin synthesis pathway, in asteraceae
por: Chen, Shiyu, et al.
Publicado: (2023)

The presence of amorpha-4, 11-diene synthase, a key enzyme in artemisinin production in ten Artemisia species
por: Hosseini, R., et al.
Publicado: (2011)

Dynamic control of ERG9 expression for improved amorpha-4,11-diene production in Saccharomyces cerevisiae
por: Yuan, Jifeng, et al.
Publicado: (2015)

High-Level Production of Amorpha-4,11-Diene, a Precursor of the Antimalarial Agent Artemisinin, in Escherichia coli
por: Tsuruta, Hiroko, et al.
Publicado: (2009)

Photosynthetic conversion of CO(2) to farnesyl diphosphate-derived phytochemicals (amorpha-4,11-diene and squalene) by engineered cyanobacteria
por: Choi, Sun Young, et al.
Publicado: (2016)

Statistical Experimental Design Guided Optimization of a One-Pot Biphasic Multienzyme Total Synthesis of Amorpha-4,11-diene
por: Chen, Xixian, et al.
Publicado: (2013)

Flavonoid Versus Artemisinin Anti-malarial Activity in Artemisia annua Whole-Leaf Extracts
por: Czechowski, Tomasz, et al.
Publicado: (2019)

Isolation and Characterization of Three New Monoterpene Synthases from Artemisia annua
por: Ruan, Ju-Xin, et al.
Publicado: (2016)

Emergence of terpene cyclization in Artemisia annua
por: Salmon, Melissa, et al.
Publicado: (2015)

Editorial: Anticancer Potential of Artemisia annua
por: Kolesar, Jill M., et al.
Publicado: (2022)

Aging affects artemisinin synthesis in Artemisia annua
por: Li, Jiao, et al.
Publicado: (2021)

Sesquiterpenes from Artemisia annua and Their Cytotoxic Activities
por: Han, Xiao, et al.
Publicado: (2022)

Studies on the Expression of Sesquiterpene Synthases Using Promoter-β-Glucuronidase Fusions in Transgenic Artemisia annua L
por: Wang, Hongzhen, et al.
Publicado: (2013)

Molecular Characterization of the 1-Deoxy-D-Xylulose 5-Phosphate Synthase Gene Family in Artemisia annua
por: Zhang, Fangyuan, et al.
Publicado: (2018)

Dried Whole Plant Artemisia annua as an Antimalarial Therapy
por: Elfawal, Mostafa A., et al.
Publicado: (2012)

Treatment of Iron-Loaded Veterinary Sarcoma by Artemisia annua
por: Breuer, Elmar, et al.
Publicado: (2014)

Transcriptome changes induced by abiotic stresses in Artemisia annua
por: Vashisth, Divya, et al.
Publicado: (2018)

Chloroplast genome transformation of medicinal plant Artemisia annua
por: Kaushal, Charli, et al.
Publicado: (2020)

Artemisia annua, a Traditional Plant Brought to Light
por: Septembre-Malaterre, Axelle, et al.
Publicado: (2020)

High-Level Patchoulol Biosynthesis in Artemisia annua L.
por: Fu, Xueqing, et al.
Publicado: (2021)

Effects of Artemisia annua on experimentally induced leucocytozoonosis in chickens
por: Chiang, Yu-Huan, et al.
Publicado: (2021)

Status of FPP Project D-082
por: Allardyce, B W
Publicado: (1994)

The Use of Combining Ability Analysis to Identify Elite Parents for Artemisia annua F1 Hybrid Production
por: Townsend, Theresa, et al.
Publicado: (2013)

Editorial: Artemisinin—From Traditional Chinese Medicine to Artemisinin Combination Therapies; Four Decades of Research on the Biochemistry, Physiology, and Breeding of Artemisia annua
por: Czechowski, Tomasz, et al.
Publicado: (2020)

New Sesquiterpene and Polymethoxy-Flavonoids from Artemisia annua L
por: Chu, Yang, et al.
Publicado: (2014)

Screening the Hemostatic Active Fraction of Artemisia annua L. In-vitro
por: Wang, Bochu, et al.
Publicado: (2011)

Differential transcriptome analysis of glandular and filamentous trichomes in Artemisia annua
por: Soetaert, Sandra SA, et al.
Publicado: (2013)

An Endophytic Pseudonocardia Species Induces the Production of Artemisinin in Artemisia annua
por: Li, Jie, et al.
Publicado: (2012)

Antioxidant Properties of Artemisia annua Extracts in Model Food Emulsions
por: Skowyra, Monika, et al.
Publicado: (2014)

Enhanced artemisinin yield by expression of rol genes in Artemisia annua
por: Dilshad, Erum, et al.
Publicado: (2015)

Selection and Clonal Propagation of High Artemisinin Genotypes of Artemisia annua
por: Wetzstein, Hazel Y., et al.
Publicado: (2018)

The Biosynthesis of Artemisinin (Qinghaosu) and the Phytochemistry of Artemisia annua L. (Qinghao)
por: Brown, Geoffrey D.
Publicado: (2010)

Chromatin Accessibility Is Associated with Artemisinin Biosynthesis Regulation in Artemisia annua
por: Zhou, Limeng, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_77t21l27ocgrdn6i9dcljj5bvl