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Multimodal imaging of bone metastases: From preclinical to clinical applications

Metastases to the skeletal system are commonly observed in cancer patients, highly affecting the patients' quality of life. Imaging plays a major role in detection, follow-up, and molecular characterisation of metastatic disease. Thus, imaging techniques have been optimised and combined in a mu...

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Detalles Bibliográficos
Autores principales: Ellmann, Stephan, Beck, Michael, Kuwert, Torsten, Uder, Michael, Bäuerle, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986987/
https://www.ncbi.nlm.nih.gov/pubmed/30035055
http://dx.doi.org/10.1016/j.jot.2015.07.004
Descripción
Sumario:Metastases to the skeletal system are commonly observed in cancer patients, highly affecting the patients' quality of life. Imaging plays a major role in detection, follow-up, and molecular characterisation of metastatic disease. Thus, imaging techniques have been optimised and combined in a multimodal and multiparametric manner for assessment of complementary aspects in osseous metastases. This review summarises both application of the most relevant imaging techniques for bone metastasis in preclinical models and the clinical setting.