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Increased ATP and ADO Overflow From Sympathetic Nerve Endings and Mesentery Endothelial Cells Plus Reduced Nitric Oxide Are Involved in Diabetic Neurovascular Dysfunction

Since the mechanism of human diabetic peripheral neuropathy and vascular disease in type 1 diabetes mellitus remains unknown, we assessed whether sympathetic transmitter overflow is altered by this disease and associated to vascular dysfunction. Diabetes was induced by streptozotocin (STZ)-treatment...

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Detalles Bibliográficos
Autores principales: Donoso, M. Verónica, Mascayano, M. Jesús, Poblete, Inés M., Huidobro-Toro, J. Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987002/
https://www.ncbi.nlm.nih.gov/pubmed/29896104
http://dx.doi.org/10.3389/fphar.2018.00546

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