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Vaccination With Recombinant Filamentous fd Phages Against Parasite Infection Requires TLR9 Expression
Recombinant filamentous fd bacteriophages (rfd) expressing antigenic peptides were shown to induce cell-mediated immune responses in the absence of added adjuvant, being a promising delivery system for vaccination. Here, we tested the capacity of rfd phages to protect against infection with the huma...
Autores principales: | Gomes-Neto, João F., Sartorius, Rossella, Canto, Fábio B., Almeida, Thamyres S., Dias, André A., Barbosa, Carlos-Henrique D., Melo, Guilherme A., Oliveira, Ana Carolina, Aguiar, Pedro-Henrique N., Machado, Carlos R., de Matos Guedes, Herbert L., Santiago, Marcelo F., Nóbrega, Alberto, De Berardinis, Piergiuseppe, Bellio, Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987186/ https://www.ncbi.nlm.nih.gov/pubmed/29896197 http://dx.doi.org/10.3389/fimmu.2018.01173 |
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