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Low-Copy Number Polymorphism in DEFA1/DEFA3 Is Associated with Susceptibility to Hospital-Acquired Infections in Critically Ill Patients

DEFA1/DEFA3, genes encoding human neutrophil peptides (HNP) 1–3, display wide-ranging copy number variations (CNVs) and is functionally associated with innate immunity and infections. To identify potential associations between DEFA1/DEFA3 CNV and hospital-acquired infections (HAIs), we enrolled 106...

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Detalles Bibliográficos
Autores principales:	Zhao, Jialian, Gu, Qiang, Wang, Lifeng, Xu, Weize, Chu, Lihua, Wang, Ya, Li, Zhongwang, Wu, Shuijing, Xu, Jianguo, Hu, Zhiyong, Shu, Qiang, Fang, Xiangming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987315/ https://www.ncbi.nlm.nih.gov/pubmed/29950924 http://dx.doi.org/10.1155/2018/2152650

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