Maternal overnutrition by hypercaloric diets programs hypothalamic mitochondrial fusion and metabolic dysfunction in rat male offspring

BACKGROUND: Maternal overnutrition including pre-pregnancy, pregnancy and lactation promotes a lipotoxic insult leading to metabolic dysfunction in offspring. Diet-induced obesity models (DIO) show that changes in hypothalamic mitochondria fusion and fission dynamics modulate metabolic dysfunction....

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Detalles Bibliográficos
Autores principales: Cardenas-Perez, Robbi E., Fuentes-Mera, Lizeth, de la Garza, Ana Laura, Torre-Villalvazo, Ivan, Reyes-Castro, Luis A., Rodriguez-Rocha, Humberto, Garcia-Garcia, Aracely, Corona-Castillo, Juan Carlos, Tovar, Armando R., Zambrano, Elena, Ortiz-Lopez, Rocio, Saville, Jennifer, Fuller, Maria, Camacho, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987395/
https://www.ncbi.nlm.nih.gov/pubmed/29991958
http://dx.doi.org/10.1186/s12986-018-0279-6

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