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Survival after the diagnosis of breast or colorectal cancer in the GAZA Strip from 2005 to 2014

BACKGROUND: Within a dramatic socio-political context, cancer represents a growing health burden in the Gaza Strip. We investigated the survival experience of people diagnosed with breast (BC) or colorectal (CRC) cancer from 2005 to 2014. METHODS: Data included 1360 BC cases (median age 55.1 years)...

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Autores principales: Panato, Chiara, Abusamaan, Khaled, Bidoli, Ettore, Hamdi-Cherif, Mokhtar, Pierannunzio, Daniela, Ferretti, Stefano, Daher, Mahmoud, Elissawi, Fouad, Serraino, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987449/
https://www.ncbi.nlm.nih.gov/pubmed/29866055
http://dx.doi.org/10.1186/s12885-018-4552-x
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author Panato, Chiara
Abusamaan, Khaled
Bidoli, Ettore
Hamdi-Cherif, Mokhtar
Pierannunzio, Daniela
Ferretti, Stefano
Daher, Mahmoud
Elissawi, Fouad
Serraino, Diego
author_facet Panato, Chiara
Abusamaan, Khaled
Bidoli, Ettore
Hamdi-Cherif, Mokhtar
Pierannunzio, Daniela
Ferretti, Stefano
Daher, Mahmoud
Elissawi, Fouad
Serraino, Diego
author_sort Panato, Chiara
collection PubMed
description BACKGROUND: Within a dramatic socio-political context, cancer represents a growing health burden in the Gaza Strip. We investigated the survival experience of people diagnosed with breast (BC) or colorectal (CRC) cancer from 2005 to 2014. METHODS: Data included 1360 BC cases (median age 55.1 years) and 722 CRC cases (median age: 59.5 years; 52.5% men) recorded by the Gaza Cancer Registry according to a standard protocol. Clinical information was available for cases diagnosed in 2005–2006 only. Survival probabilities were estimated by Kaplan-Meyer method, while hazard ratios (HRs) and 95% confidence intervals (CI), adjusted for age and sex, were computed to assess factors associated with the risk of death. RESULTS: Five-year survival was 65.1% for women with BC and 50.2% for patients with CRC. Advanced age (> 65 years), stage, and grade increased the death risk. Full access to therapies was associated with a reduced risk of death as compared with patients who had limited access (HR = 0.26, 95% CI:0.13–0.51 for BC; and HR = 0.11, 95% CI:0.04–0.31 for CRC). CONCLUSION(S): The 5-year survival after BC or CRC in the Gaza Strip was in line with estimates from surrounding Arab countries, but it was much lower than in developed Mediterranean countries (e.g., in Italy or in Jewish people in Israel).
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spelling pubmed-59874492018-07-10 Survival after the diagnosis of breast or colorectal cancer in the GAZA Strip from 2005 to 2014 Panato, Chiara Abusamaan, Khaled Bidoli, Ettore Hamdi-Cherif, Mokhtar Pierannunzio, Daniela Ferretti, Stefano Daher, Mahmoud Elissawi, Fouad Serraino, Diego BMC Cancer Research Article BACKGROUND: Within a dramatic socio-political context, cancer represents a growing health burden in the Gaza Strip. We investigated the survival experience of people diagnosed with breast (BC) or colorectal (CRC) cancer from 2005 to 2014. METHODS: Data included 1360 BC cases (median age 55.1 years) and 722 CRC cases (median age: 59.5 years; 52.5% men) recorded by the Gaza Cancer Registry according to a standard protocol. Clinical information was available for cases diagnosed in 2005–2006 only. Survival probabilities were estimated by Kaplan-Meyer method, while hazard ratios (HRs) and 95% confidence intervals (CI), adjusted for age and sex, were computed to assess factors associated with the risk of death. RESULTS: Five-year survival was 65.1% for women with BC and 50.2% for patients with CRC. Advanced age (> 65 years), stage, and grade increased the death risk. Full access to therapies was associated with a reduced risk of death as compared with patients who had limited access (HR = 0.26, 95% CI:0.13–0.51 for BC; and HR = 0.11, 95% CI:0.04–0.31 for CRC). CONCLUSION(S): The 5-year survival after BC or CRC in the Gaza Strip was in line with estimates from surrounding Arab countries, but it was much lower than in developed Mediterranean countries (e.g., in Italy or in Jewish people in Israel). BioMed Central 2018-06-04 /pmc/articles/PMC5987449/ /pubmed/29866055 http://dx.doi.org/10.1186/s12885-018-4552-x Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Panato, Chiara
Abusamaan, Khaled
Bidoli, Ettore
Hamdi-Cherif, Mokhtar
Pierannunzio, Daniela
Ferretti, Stefano
Daher, Mahmoud
Elissawi, Fouad
Serraino, Diego
Survival after the diagnosis of breast or colorectal cancer in the GAZA Strip from 2005 to 2014
title Survival after the diagnosis of breast or colorectal cancer in the GAZA Strip from 2005 to 2014
title_full Survival after the diagnosis of breast or colorectal cancer in the GAZA Strip from 2005 to 2014
title_fullStr Survival after the diagnosis of breast or colorectal cancer in the GAZA Strip from 2005 to 2014
title_full_unstemmed Survival after the diagnosis of breast or colorectal cancer in the GAZA Strip from 2005 to 2014
title_short Survival after the diagnosis of breast or colorectal cancer in the GAZA Strip from 2005 to 2014
title_sort survival after the diagnosis of breast or colorectal cancer in the gaza strip from 2005 to 2014
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987449/
https://www.ncbi.nlm.nih.gov/pubmed/29866055
http://dx.doi.org/10.1186/s12885-018-4552-x
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